The Science behind Coolzen

Why Hot Flushes happen

Women hit menopause over a transition period of 3-5 years which is called perimenopause. It is during this transition, that hormonal changes occur in the body.Our bodies generally exist within a “thermoneutral zone,” where we’re not shivering or sweating. Menopause narrows that zone, so slight alterations in body temperature can cause sweating. Decreasing reproductive hormone levels has something to do with this change, but its exact role isn’t well understood. This change results in hot flushes that present themselves as a physiological phenomenon marked by sudden sensations of warmth around the neck, chest, and face regions. Symptoms often include rapid heart rate, persistent sweating, and flushing of your skin.

Figure 1. Graph depicting a narrowing "thermoneutral zone" during Perimenopause

Source: Real Health in Focus: Menopause Series.

How Coolzen works

Detection of hot flushes: Coolzen adopts a sophisticated strategy to drive out the discomfort associated with hot flushes. It integrates continuous body temperature monitoring for hot flush detection. By harnessing our proprietary algorithm, Coolzen accurately identifies the onset of hot flushes.

Disruption of hot flushes: The nape of the neck is particularly responsive to cooling sensations. Coolzen leverages this physiological response of the human body and precisely delivers cooling to this strategic region. By doing this, Coolzen tricks the brain into assuming that the natural cooling mechanism of the body i.e. flushing of the skin and sweating, has worked and the body temperature has dropped. Having been tricked into achieving this, the brain reigns in the body’s natural cooling mechanism i.e flushing of the skin and sweating, resulting in a rapid and effective disruption of hot flush episodes.

Importance of automation: The use of a proprietary algorithm for the automatic detection of hot flush onset empowers Coolzen to offer accurate, timely, and personalised relief from hot flushes. This approach represents a significant advancement in hot flush management, promising enhanced comfort and well-being for individuals experiencing hot flushes. Automatic detection ensures that Coolzen seamlessly integrates into the user's daily life without any need for manual intervention or interruption of activities during the day. In addition, Coolzen prevents sleep disruption improving general wellness, productivity, emotional well-being and reducing fatigue.

Our user data shows that Coolzen is effective in reducing both the intensity and duration of hot flushes. In the case of detection of hot flushes, Coolzen has been successful in detecting hot flushes in over 85% of instances. The exceptions to this have been observed in cases where hot flushes do not present themselves as expected changes in body temperature.